Results 111 to 120 of about 430,868 (306)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Optimal Income Taxation and Public Goods Provision in a Large Economy with Aggregate Uncertainty [PDF]
We study a large economy model in which individuals have private information about their productive abilities and their preferences. Moreover, there is aggregate uncertainty so that the social benefits from taxation and public goods provision are a ...
Felix Bierbrauer
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Decentralised Provision of Quasi- Private Goods: The Case of Colombia [PDF]
This paper quantifies the welfare effects of decentralisation in Colombia, using a multiregional CGE model.We investigate to what extent will the Colombian Population be better off when goods such as health and education, are delivered locally as against
Ana María Iregui
core
, 2020 Sociālais darbsSociālā labklājībaSocial workSocial WelfareSociālo pakalpojumu un sociālās palīdzības paredzamais nodrošinājums Skrīveru novadā pēc administratīvi teritoriālās reformas.
Edvarts Pāvulēns
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Replication materials for "Information Provision, Voter Coordination, and Electoral Accountability: Evidence from Mexican Social ...
Querubin, Pablo +4 more
core +2 more sources
Children’s rights in social work practice: Theory, protection, participation and provision
This is an Accepted Manuscript of a book chapter published by Routledge in [Children’s rights in social work practice: Theory, protection, participation and provision] on [date of publication], available online: http://www.routledge.com/[BOOK ISBN URL]In
Dillon, Jo
core
, 2005 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.It is recognised that looked after young people with a history of trauma, offending, emotional, behavioural and educational difficulties often face a high ...
Brady, Lynn
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source