Results 121 to 130 of about 2,062,933 (307)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Economics of Corporate Social Responsibility (CSR): Selling to Someone who Has Personal Valuation [PDF]
This paper provides general insight on the economic feasibility and desirability of Corporate Social Responsibility (CSR), in order to explain why some firms voluntarily over comply with social matters. In this paper I define CSR as the activity in which
Martin Daniel Siyaranamual
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Why Praise Inequality? Public Good Provision, Income Distribution and Social Welfare [PDF]
We consider a two-person Cournot game of voluntary contributions to a public good with identical individual preferences, and examine equilibrium aggregate welfare under a separable, symmetric and concave social welfare function.
Indraneel Dasgupta
core
A Multi-Task Theory of the State Enterprise Reform [PDF]
, 2001 During transition, maintaining employment and providing a social safety net to the unemployed are important to social stability, which in turn is crucial for the productivity of the whole economy.
Bai, Chong-En +3 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
MANAGEMENT OF THE STABLE DEVELOPMENT OF SOCIAL-ECONOMIC SYSTEM: INSTITUTIONAL ASPECTS
Russian Journal of Economics and Law, 2012 The article views institutional transformations aimed at stable development provision; defines a number of basic institutional problems barring the efficient management of stable development; grounds the necessity of further institutional transformations
E. A. Tretyakova, T. V. Alferova
doaj
BMC PsychologyBackground A growing body of research suggests that the provision of social support can have benefits not only for the recipients but also for the provider.
Vivien Hajak +5 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
International Journal of Population Data ScienceObjective and Approach Pupils ‘Educated in Other Than At School’ (EOTAS) are some of the most vulnerable learners, who, for reasons such as mental health or behavioural difficulties, do not attend a mainstream school.
Olivier Y. Rouquette +3 more
doaj +1 more source