Results 151 to 160 of about 430,868 (306)

Status Effects, Public Goods Provision, and the Excess Burden

Most studies of the optimal provision of public goods or the excess burden from taxation assume that individual utility is independent of other individuals' consumption.
Wendner, Ronald, Goulder, Lawrence H.
core  

Optimal Income Taxation and Public-Goods Provision with Preference and Productivity Shocks [PDF]

We study how an optimal income tax and an optimal public-goods provision rule respond to preference and productivity shocks. A conventional Mirrleesian treatment is shown to provoke manipulations of the policy mechanism by individuals with similar ...
Felix Bierbrauer
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Financial well-being advice delivered within the context of social prescribing in the UK and the Republic of Ireland. [PDF]

Front Public Health
Newstead S, Jesurasa A, Jenkins B, Filipponi T, Oloidi E, Makanjuola A, Wallace C.   +6 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Cost-effectiveness of school-based interventions for well-being and mental health literacy of pupils in year 9 in England: AWARE cluster randomised controlled trial. [PDF]

BJPsych Open
Zhang K, King D, Boehnke J, Deighton J, Thompson A, Thornton E, Knowles C, Hayes D, Stallard P, Santos J, Ashworth E, Evans-Lacko SE.   +11 more
europepmc   +1 more source

Retirement provision for New Zealand women: The relative role of demographic influence

, 1999
This research contributes to our knowledge of retirement provision by clarifying the obstacles that women face in relation to old age provision. By using multivariate analysis and therefore by controlling for confounding effects, this study has isolated ...
Marsault, Anyes
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Women's social care provision in prison has improved but challenges remain: findings from a national survey in England eight years after the 2014 Care Act. [PDF]

BMC Public Health
Buck D, O'Neill A, Marsh N, Stalker K, Plugge E, Hargreaves C, Brimblecombe N, Harriott P, Robinson C, Shaw JJ, Forsyth K.   +10 more
europepmc   +1 more source

Privatisation policy and the delivery of social welfare services in Africa : a Nigerian example

, 1999
The paper examines the underlying conceptual and theoretical logic of the policy of privatisation in the area of social welfare services, and its unfolding empirical manifestations in Africa, with a Nigerian example.
Adejumobi, Said
core