Results 161 to 170 of about 332,506 (260)

A Europe-wide provider perspective of healthcare services for adolescent and young adult patients with haematological conditions: a survey from the Adolescent and Young Adult Taskforce of the European Hematology Association. [PDF]

EClinicalMedicine
Schoenaker MHD, Veal C, Batten S, Boissel N, Borowczak Y, Colombatti R, Doeswijk R, Hilgendorf I, McGrath C, Messelink K, Miano M, Yacobovich J, Vormoor J, Castleton A.   +13 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Medicare Advantage's Provision of Expanded Supplemental Benefits and Acute Care Utilization. [PDF]

Health Serv Res
Jung J, Song G, Feldman R, Carlin C, Polsky D, Kim H.   +5 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Economic evaluation of hearing aid use and quality of life in older adults with hearing impairment in India. [PDF]

Front Med Technol
Sahoo RK, Sahoo KC, Pattanayak U, Sinha A, Jena A, Aimol LW, Rajsekar K, Bhattacharya D, Pati S.   +8 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

COVID-19 legislative response and challenges in Republic of Korea. [PDF]

Front Public Health
Shin HY, Ki M.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of interventions addressing perinatal mental health on loneliness and/or satisfaction with social support: systematic review. [PDF]

BMC Psychiatry
Vasquez C, D'souza AR, Nowland R, Taylor BL, Adlington K, Pearce E, Pitman A.   +6 more
europepmc   +1 more source