Results 121 to 130 of about 1,884,358 (314)

Environmental Sustainability as Indicator of Social Quality The New Opportunities Offered by Communication

open access: yes, 2014
Compared to the European scenario that emerged from the analysis of Eurobarometer (2011–2014) surveys, we conducted a research on the opinions of the Italian students and professionals from eight focus groups about the relation between environmental ...
FERRUCCI, MARTINA, FONTANA, Renato
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Social Support and Sex Role Orientation as Predictors of Quality of Life in Senior Citizens

open access: yes, 2020
The present study was aimed to explore the relationship of social support and sex role orientation with quality of life in senior citizens The sample comprised of 400 senior citizens with equal number of educated males and females 200 each The ...
Yajvinder, Dr. Anita Sharma
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Agritourism in academic research: Literature review and cluster analysis

open access: yesTourism
The aim of the article is to review the current literature in the field of agritourism. The data for the analysis was collected from the Web of Science database from 1990–2022: a total of 1,834 bibliometric publication records.
Michał Roman, Norbert Kawęcki
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

VARIATION OF LIFE QUALITY AND SOCIAL FUNCTIONING INDICATION IN PATIENTS WITH SCHIZOPHRENIA ACCORDING TO TREATMENT RESPONSE

open access: yes, 2016
Background: To conduct a comparative analysis of indicators of life quality and social functioning in patients with schizophrenia according to the received treatment.
Barylnik, Julia   +6 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Quality Assessment of Social Services

open access: yes, 2021
Sociālais darbsSociālā labklājībaSocial workSocial WelfareAtslēgas vārdi: kvalitātes novērtēšana, kvalitātes rādītāji, administratīvi teritoriālā reforma. Bakalaura darba autore ir Megija Pētersone.
Megija Pētersone
core  

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