Results 141 to 150 of about 136,465 (300)

Quantifying Social Capital At School [PDF]

open access: yes, 2009
From introduction: Because schools operate in such complex environments the effects of various forms of social capital on outcomes is difficult to delineate without careful and detailed analysis.
Catts, Ralph
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Quantification des fibrés des états.

open access: yes, 2015
On se propose de quantifier les fibrés hermitiens à fibre séparable. On s'intéresse à la quantification d'un état de l'univers Ω en généralisant l'axiomatique de quantification aux sections du fibré.
Jonot, Jean Louis
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Social Informatics in Slovenia: Between Traditional Understanding and Unrealised Opportunities [PDF]

open access: yesDružboslovne Razprave
Social Informatics was established in 1984 as the first academic programme in the world with this title. Parallel to this, Social Informatics as a specific scientific activity at the intersection of sociology, computer science, and social science ...
Gregor Petrič
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Socio-ecological metabolism of cities: conceptualization, research schools, and modern foreign studies

open access: yesСоциологическая наука и социальная практика, 2016
The author of the article provides an overview of the original sources for the study of the conceptual foundations of socio-ecological metabolism of cities, as well as analysis of its basic schools, representatives and areas of modern scientific research.
Polina O. Ermolaeva
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

The Politics of Governance by Quantification Infrastructure

open access: yes
Governance by quantification has a long history in human society. However, two critical issues remain underexplored in the sociology of quantification.
Liu, Chuncheng, Liu, Jun
core   +1 more source

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