Results 161 to 170 of about 340,207 (263)
Social representation of hearing aids: cross-cultural study in India, Iran, Portugal, and the United Kingdom. [PDF]
Manchaiah V +6 more
europepmc +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Social representations of European Union
Çalısmanın temel amacı Avrupa Birligi ile ilgili baskın sosyal temsillerin ortayaçıkarılmasıdır. Amaca yönelik ilk olarak demografik yönden birbirlerinden farklı 13 kisi ileyarı yapılandırılmıs görüsmeler yapılmıs ve yapılan içerik analizi sonucunda Türkiye'nin ABüyeligi, Türkiye'nin problemleri, AB'nin yapısı, AB'nin dezavantajları
openaire +2 more sources
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
From Portuguese Colonial Representations to Racist Endorsement: Investigating Correlational and Causal Paths. [PDF]
Meuer F +3 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The notion of common and social representations
openaire +3 more sources
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source

