Results 101 to 110 of about 1,023,924 (350)

Sintomatologia depressiva em adolescentes do ensino médio: um estudo das representações sociais

Psicologia: Ciência e Profissão
A depressão é uma das psicopatologias que vêm avançando nas demandas da saúde coletiva e ocorre em qualquer idade, independentemente da inserção socioeconômica e cultural. O presente trabalho teve como objetivo apreender as representações sociais (RS) da
Fabiana Ribeiro Monteiro, Maria da Penha de Lima Coutinho, Ludgleydson Fernandes de Araújo   +2 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

A teacher preparation course in the social representation construction concerning being teacher of Chemistry [PDF]

Investigações em Ensino de Ciências, 2015
The role of a pre-service teacher education in a construction of social representation about being teacher is the topic of this study, which included the participation of 44 first year and 27 last year undergraduate students from a course of chemistry.
Camila Lima Miranda, Daisy de Brito Rezende, Julio Cezar Foschini Lisbôa   +2 more
doaj  

Social representations of teachers on family and their role in school/Representaciones sociales de los maestros sobre la familia y su rol en la escuela [PDF]

, 1970
Iván Darío Moreno Acero, Alexandra Bermúdez Saray, Jeimy Dayan Ramos Páez, Claudia Ximena Mora Pacheco, Diana Marcela Torres   +4 more
openalex   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

The Social Representation Paradigm

THE JAPANESE JOURNAL OF EXPERIMENTAL SOCIAL PSYCHOLOGY, 1996
This paper presents a brief overview of the social representation approach. Relevant content-oriented as well as theory-driven research and their implications are presented. Some critical topics in the ongoing debate among scholars are presented and important future foci of research are discussed. The paper includes an extensive bibliography.
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Social Representations and Female Unemployment: Shared Meanings in Process of Transformation?

Psicologia, 2004
While some research copes with the problem of unemployment from a purely economic perspective, underlying thus the number of unemployed, other research focus more on the consequences of the unemployment for the individual.
José Francisco Valencia , Maider Larrañaga   +1 more
doaj  

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source