Results 101 to 110 of about 7,977,391 (314)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Violent social norms: a study on the symbolic elaboration of violence in adolescents / Norma social violenta: um estudo da representação social da violência em adolescentes

Psicologia: Reflexão e Crítica, 2007
The present work approaches teenage violence, exploring the consensual field of social representation and identifying some elements that act as guiders and justifiers of violent action.
Silvia Pereira Guimarães, Pedro Humberto Faria Campos   +1 more
doaj  

Social representations of nutrition: proposal production of teaching materials chemistry [PDF]

Investigações em Ensino de Ciências, 2013
In this paper, we present the stages of production of didactic material of Chemistry (thematic unit on nutrition), and the results of its application in a classroom of basic education.
Carlos Ventura Fonseca , Rochele de Quadros Loguercio   +1 more
doaj  

Social representations of cancer in patients from Medellín, Colombia: a qualitative study. [PDF]

Front Sociol, 2023
Higuita-Gutiérrez LF, Estrada-Mesa DA, Cardona-Arias JA.   +2 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

UM ESTUDO DAS REPRESENTAÇÕES SOCIAIS DE ESTUDANTES DO ENSINO MÉDIO SOBRE OS INSETOS

Ensaio Pesquisa em Educação em Ciências
O objetivo do estudo foi identificar as representações sociais construídas pelos estudantes do Ensino Médio em relação aos insetos. A coleta de dados foi realizada por meio da aplicação de questionários junto a 100 estudantes de duas escolas públicas.
Oziel Santana Neri Trindade, Juvenal Cordeiro Silva Júnior, Paulo Marcelo Marini Teixeira   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Imprisoned Women and Prison Universe: A Social Representations Analyses

Psicologia, 2005
The objective of this work was to investigate the social representations of the prison space of women inmates in a State Female Penitentiary. For this study, we opted for a semi-structured interview as data collection instrument.
Fernanda de Magalhães Dias Frinhani, Lídio de Souza   +1 more
doaj  

Social Representations and the Politics of Participation [PDF]

, 2014
Caroline Howarth, Eleni Andreouli, Shose Kessi   +2 more
openalex   +1 more source