Results 121 to 130 of about 9,372,448 (341)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Social representations and professional training practices

open access: yesAssensus, 2017
This article shows the results of the research project “Student social representations of the student practices of the Physic Education of the University of Córdoba and Social work of the University of Quindío”. Inside of it, it is showed the practice as
Fernando Antonio de La Espriella Arenas   +1 more
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Parents' social representations about adolescents' leisure

open access: yesCultura, Ciencia y Deporte, 2011
En los Estados Unidos de América hay tres posiciones filosóficas antes de la recreación de los adolescentes (Larson y Seepersad, 2003): las actividades no estructuradas, las actividades estructuradas y la combinación de estas dos.
Antonino Manuel de Almeida Pereira
doaj  

Representations of Social Europe

open access: yes, 2014
Two main political and economic paradigms have framed the Social Europe so far. The first one has consisted in the (German) "ordoliberalism", which has played a key role in structuring the foundations of the European Community as well as those of the Monetary Union.
Lechevalier, Arnaud   +3 more
openaire   +3 more sources

Madness in a 'secret region': extended notes on Denise Jodelet's 'Madness and Social Representations [PDF]

open access: yes, 2001
Paper associated with research for ESRC-funded research project 'Social Geographies of Rural Mental Health' (R000 23 ...
Philo, Christopher
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The “Audacity” of Visibility: Preta-Rara’s Feminist Praxis [PDF]

open access: yes, 2019
In this article, I examine the formidable array of artistic production and advocacy work by Preta-Rara, a feminist rapper from São Paulo, Brazil, especially her use of social media and her music, in which she mobilizes feminist discourses to challenge ...
Perrine, Alida Louisa
core  

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