Results 151 to 160 of about 109,239 (263)

Civil society perspectives on tuberculosis care for people living with HIV in Brazil: A study informed by Social Representations Theory. [PDF]

open access: yesPLOS Glob Public Health
Magnabosco GT   +10 more
europepmc   +1 more source

Socioenvironmental conflicts and social representations surrounding mining extractivism at Santurban. [PDF]

open access: yesSci Rep, 2022
Zárate-Rueda R   +2 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Information on latent tuberculosis infection in higher education: social representations of nursing students. [PDF]

open access: yesRev Esc Enferm USP
Andrade EGR   +7 more
europepmc   +1 more source

Social Representations of Urinary Incontinence in Caregivers and General Population: A Focus Group Study. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Peroni L   +3 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Social representations of COVID-19 by the nursing team of an intensive care unit. [PDF]

open access: yesBMC Nurs
da Silva RC   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy