Results 51 to 60 of about 1,403,691 (308)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Equity and the social reproduction of capital [PDF]

open access: yes, 2017
This essay draws on Marxist thinking to argue that equity is essential to the social reproduction of finance capital. Equitable doctrines can be seen as assemblages that define and reproduce the way in which money, people and property relate to each ...
Hu, J   +6 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Hakikat Dan Nuansa Ketahanan Sosial Masyarakat Banyumas Dalam Lensa Reproduksi Sosial

open access: yesJurnal Ketahanan Nasional
The Covid-19 epidemic requires strengthening community resilience to adapt to changing social situations. The research aims to find out the nature and nuances of the dynamics of social resilience in the Banyumas community through changes in priorities ...
Shinta - Prastyanti
doaj   +1 more source

Human sense and plant blindness

open access: yesLanguage and Semiotic Studies, 2023
Victoria Welby introduces the concept of “Significs” as a methodology that could bridge the various sciences, theoretical trends, and practices in human experience.
Dellino Dario
doaj   +1 more source

Social aspects in assisted reproduction [PDF]

open access: yesHuman Reproduction Update, 1999
In-vitro fertilization (IVF) and assisted reproductive techniques have become common practice in many countries today, regulated by established legislation, regulations or by committee-set ethical standards. The rapid evolution and progress of these techniques have revealed certain social issues that have to be addressed.
S J, Fasouliotis, J G, Schenker
openaire   +2 more sources

Harnessing the social: state, crisis and (big) society [PDF]

open access: yes, 2014
The paper analyses the UK government’s plans to create a social investment market. The Big Society as political economy is understood as a response to three aspects of a multi-faceted, global crisis: a crisis of capital accumulation; a crisis of social ...
Bishop M   +22 more
core   +1 more source

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