Results 71 to 80 of about 1,400,192 (305)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Aspects of Sex Differences: Social Intelligence vs. Creative Intelligence [PDF]
, 2017 In this article, we argue that there is an essential difference between social intelligence and creative intelligence, and that they have their foundation in human sexuality.
Fellmann, Ferdinand +1 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Equity and the social reproduction of capital [PDF]
, 2017 This essay draws on Marxist thinking to argue that equity is essential to the social reproduction of finance capital. Equitable doctrines can be seen as assemblages that define and reproduce the way in which money, people and property relate to each ...
Hu, J +6 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
BOLSA FAMÍLIA X SALÁRIO NA REPRODUÇÃO SOCIAL DE FAMÍLIAS POBRES EM BELÉM (PA)
Revista de Políticas Públicas, 2018 This article presents the main results and analysis from master’s thesis com- pleted this year, whose aim was to understand how the incomes of labor and Family Grant Program combine or conflict in the social reproduction of the be- neficiaries and the ...
Olga Myrla Tabaranã Silva +1 more
doaj
Schooled for Servitude: The Education of African Children in British Colonies, 1910–1990
Genealogy, 2019 Our paper examines the education of African children in countries that were colonized by Britain, including Ghana, South Africa, and Zimbabwe. We show how education plays an important role in shaping and transforming cultures and societies.
Mark Malisa, Thelma Quardey Missedja
doaj +1 more source
Marriage choices and social reproduction [PDF]
This article studies the relationship between partner selection and socioeconomic status (SES) attainment and mobility in five rural parishes in southern Sweden, 1815-1894.
Christer Lundh, Martin Dribe
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Politicizzare la cura per curare la democrazia
SocietàMutamentoPolitica: Rivista Italiana di Sociologia“Taking care” involves a politics of relationships. Care has both a subjective and a relational dimension: starting from subjectivity, everyone opens up to vulnerability, dependence, fragility. Care is above all a practical path of spillage from the self
Sara Fariello, Irene Strazzeri
doaj +1 more source