Results 81 to 90 of about 1,392,816 (307)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Reproducing Elite Lives: Women in Aggarwal Family Businesses
South Asia Multidisciplinary Academic Journal, 2017 This article explores the social reproductive roles performed by elite “upper”-caste Aggarwal women in family businesses in Delhi. With the substantialization of caste, there is an increase in heterogeneities within caste groups.
Ujithra Ponniah
doaj +1 more source
The mating behavior and reproduction performance in a multi-sire mating system for pigs [PDF]
, 2008 An important aim of organic animal production is to allow natural animal behaviour. Regarding reproduction techniques, artificial insemination is permitted but natural mating is preferred.
Hermansen, J.E., Kongsted, A.G.
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
On tradition, communication and social reproduction [PDF]
, 2015 In ‘Overcoming Resistance to Cultural Studies,’ Carey writes, how is it, through all sorts of change and diversity, through all sorts of conflicts and contradiction, that the miracle of social life is pulled off, that societies manage to produce and ...
Mangion, Claude
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Politics of the Algorithm: Technologies, Powers, Theories
Scienza & PoliticaThe introduction to the monographic section Politics of the Algorithm: Technologies, Powers, Theories, examines the nexus between technology and politics from the way in which the former, and algorithm-driven technologies in particular, has irreversibly ...
Isabella Consolati, Paola Rudan
doaj +1 more source
'Mamlukisation' between social theory and social practice: an essay on reflexivity, state formation, and the late medieval sultanate of Cairo [PDF]
, 2015 This working paper is a reflexive essay that tries to think with and beyond one of the basic assumptions upon which the field of late medieval Syro-Egyptian ‘Mamluk’ studies is built: the idea that all late medieval Syro-Egyptian objects of study are by ...
Van Steenbergen, Jo
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source