Results 81 to 90 of about 1,403,691 (308)

Dairy Joint Ventures in South Africa’s Land and Agrarian Reform Programme: Who Benefits?

open access: yesLand, 2020
Joint Ventures (JVs) between ‘agribusiness’ investors and ‘small farmers’ or ‘customary landowners’ are being promoted in South Africa’s land and agrarian reform programme as a way to include land reform beneficiaries in the country’s competitive ...
Brittany Bunce
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Reproducing Elite Lives: Women in Aggarwal Family Businesses

open access: yesSouth Asia Multidisciplinary Academic Journal, 2017
This article explores the social reproductive roles performed by elite “upper”-caste Aggarwal women in family businesses in Delhi. With the substantialization of caste, there is an increase in heterogeneities within caste groups.
Ujithra Ponniah
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

'Mamlukisation' between social theory and social practice: an essay on reflexivity, state formation, and the late medieval sultanate of Cairo [PDF]

open access: yes, 2015
This working paper is a reflexive essay that tries to think with and beyond one of the basic assumptions upon which the field of late medieval Syro-Egyptian ‘Mamluk’ studies is built: the idea that all late medieval Syro-Egyptian objects of study are by ...
Van Steenbergen, Jo
core  

Self-identity, embodiment and the development of emotional resilience [PDF]

open access: yes, 2013
This article is made available through the Brunel Open Access Publishing Fund. Copyright @ The Author 2013. Published by Oxford University Press on behalf of The British Association of Social Workers.
Bonanno   +9 more
core   +4 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Politics of the Algorithm: Technologies, Powers, Theories

open access: yesScienza & Politica
The introduction to the monographic section Politics of the Algorithm: Technologies, Powers, Theories, examines the nexus between technology and politics from the way in which the former, and algorithm-driven technologies in particular, has irreversibly ...
Isabella Consolati, Paola Rudan
doaj   +1 more source

On tradition, communication and social reproduction [PDF]

open access: yes, 2015
In ‘Overcoming Resistance to Cultural Studies,’ Carey writes, how is it, through all sorts of change and diversity, through all sorts of conflicts and contradiction, that the miracle of social life is pulled off, that societies manage to produce and ...
Mangion, Claude
core  

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