Results 91 to 100 of about 2,426,340 (264)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

La entrevista como encuentro dialógico. Aportes del Círculo de Bajtín para pensar la técnica de producción de datos

open access: yesEMPIRIA: Revista de Metodología de Ciencias Sociales
La entrevista es una técnica utilizada en distintos campos, como el periodístico, la clínica, el policial, etc. Además, es una de las herramientas preferidas dentro de las investigaciones cualitativas. Tal como sostienen algunos autores, la entrevista es
María Belén Angelelli
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Polish Society's Perspective on the Challenges Related to Childhood Cancer: Analysis of Public Opinion Research in Poland

open access: yesCancer Reports
Background Treatment of children diagnosed with cancer requires coordinated, multimodal therapy that is often resource intensive and can occur over several years.
J. Pruban   +7 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Uncovering platforms: investigating and visualizing the variety of platform capitalism in Italy and Spain.

open access: yesCambio
This paper critically examines the phenomenon of platform capitalism through the lens of national contextual factors that shape its evolution, challenging the prevailing tendency in the literature to emphasize convergence towards a uniform North ...
Massimo De Minicis
doaj   +1 more source

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