Results 81 to 90 of about 5,212,449 (312)

Harmonizing cross-cultural and transdiagnostic assessment of social cognition by expert panel consensus

open access: yesSchizophrenia
Social cognition, the perception and processing of social information, is adversely affected in multiple psychiatric, neurological, and neurodevelopmental disorders, and these impairments negatively impact quality of life for individuals across the globe.
Amy E. Pinkham   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Methodological Nationalism in the Social Sciences: Consequences for Social Science Research

open access: yesMigracijske i etničke teme, 2011
Social scientists are becoming increasingly aware of the fact that human society cannot and should not be equated with the “national society”, an imagined aggregate of social relations within the boundaries of nation-states.
Simona Kuti, Saša Božić
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Nóesis: un oasis intelectual en el desierto chihuahuense

open access: yesNóesis, 2009
Durante dos décadas, la revista académica Nóesis ha sido uno de los oasis intelectuales de la investigación científica social en el estado de Chihuahua. Su trayectoria durante estos veinte años constituye, primero, un reconocimiento de nuestro rezago en ...
Luis Antonio Payán Alvarado
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Methodology and Key Issues of ISSP Environment Research Project from Sustainable Development Perspective

open access: yesProblemy Ekorozwoju, 2010
The article presents the issues and methodology employed in a cross-national research program – the International Social Survey Program (ISSP) Environment.
Paweł Rydzewski
doaj  

La ricerca sociale pubblica in Italia attraverso i percorsi di istituzionalizzazione: una ricostruzione introduttiva

open access: yesCambio
This introductory essay examines the development and nuances of public social research in Italy, focusing on the influence and reception of Michael Burawoy’s ideas and the institutionalization of public sociology in the Italian context.
Paolo Diana, Giovannipaolo Ferrari
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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