Results 41 to 50 of about 5,212,449 (312)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Scottish Social Attitudes Survey, 2019

open access: yes, 2023
copyright UK Data Service and data collection copyright owner.The Scottish Social Attitudes (SSA) survey was launched by ScotCen Social Research (formerly the Scottish Centre for Social Research) in 1999, following the advent of devolution.
ScotCen Social Research
core  

Application of logit regression models for the identification of market segments

open access: yesJournal of Business Economics and Management, 2007
A success of the currently implemented projects and measures is determined not only by the urgency and soundness of idea and the size of the budget, but also by the direction of resources to those users and organizations, from which the largest return ...
Marija Burinskienė, Vitalija Rudzkienė
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Scottish Social Attitudes Survey, 2017

open access: yes, 2023
copyright UK Data Service and data collection copyright owner.The Scottish Social Attitudes (SSA) survey was launched by ScotCen Social Research (formerly the Scottish Centre for Social Research) in 1999, following the advent of devolution.
ScotCen Social Research
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Review: Barbara Merril & Linden West (2009). Using Biographical Methods in Social Research

open access: yesForum: Qualitative Social Research, 2011
The return of the subject in the social sciences reflects growing interest in the study of subjectivity. This refers to opportunities for individuals to make meaning of their lives within the institutions of society.
Vanessa Garcia Diaz
doaj  

El pensamiento ambiental como génesis de la bioética en la investigación social

open access: yesDictamen Libre, 2016
As part of the biosphere the human species has focused special attention to the nature of the inter- feedbacks that are syste-mism understanding existing between the various species and how all human action creates a chain reaction in every sphere of ...
Lina Marcela Sánchez Vásquez
doaj   +1 more source

Digital adaptation issues for different demographics in Russian Moscow region

open access: yesВестник университета, 2020
The article aims to analyze the adaptation specifics of four generations to digital technologies in Russian Moscow region. The research theoretical basis consists of the basic socio-demographic generations description within the William Strauss and Neil ...
L. G. Akhmaeva   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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