Results 231 to 240 of about 430,343 (300)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Reciprocal effects between post-migration risk factors for mental health and barriers to access to treatment among refugees and asylum seekers: what have we learnt? [PDF]

Front Psychiatry
Bartolomei J, Reyre A.
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Future impacts of colectomy healthcare pathways on quality of care in bundled payment experiments, a national retrospective cohort in France. [PDF]

PLoS One
Sanchez MA, Mercier G, Clément MC, Ortega-Deballon P, Sanchez S, Quantin C.   +5 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Financing strategies for contract agricultural supply chain considering government subsidized interest. [PDF]

PLoS One
Wang J, Li C, Shi Y.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Factors influencing customers' switching intentions to new energy vehicles based on the push-pull mooring model using SEM-ANN approach in Shanxi, China. [PDF]

Sci Rep
Juanjuan Z, Rasiah R.
europepmc   +1 more source

Factors Influencing Adherence to All-Oral Short-Course Treatment for DR-TB and Establishment of a Predictive Model. [PDF]

Infect Drug Resist
Huang J, Zhu QD, Li ZF, Xie K, Deng JN, Ma QY, Su HZ, Lu TT, Lu XF, Hu YL, Xie ZH.   +10 more
europepmc   +1 more source

Research on the threshold of the supply and demand of ecosystem services. [PDF]

PLoS One
Deng H, Liao Z, Zhou X.
europepmc   +1 more source