Results 111 to 120 of about 12,811,924 (312)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Corporate Social Responsibility and Corporate Financial Performance: Evidence from Korea [PDF]

open access: yes
This paper studies the empirical relation between corporate social responsibility (CSR) and corporate financial performance in Korea using a sample of 1122 firm-years during 2002-2008.
Choe, Chongwoo   +2 more
core  

An Evaluation of Social Responsibility Practices in selected Corporate Units [PDF]

open access: yes, 2007
Corporate social responsibility has become a favourite topic of discussion for businessmen, academicians, political leaders, social reformers and management students in India.
Joshi, Bhargav B.
core  

The contemporary definition of university social responsibility with quantifiable sustainability

open access: yes, 2019
Purpose The university social responsibility (USR) is still in embryonic stage compared to corporate social responsibility (CSR) which is still debatable by researchers.
Kouatli, Issam
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Business for Social Responsibility Homepage

open access: yes
A nonprofit organization, Business for Social Responsibility (BSR) provides information, tools, training and advisory services to make corporate social responsibility an integral part of business operations and ...

core   +2 more sources

UNO Website: UNO Civic and Social Responsibility Homepage [PDF]

open access: yes, 2016
UNO Website: Civic and Social Responsibility, Fall 2016 Job ...
University of Nebraska at Omaha, UNO Civic and Social Responsibility
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

CORPORATE SOCIAL RESPONSIBILITY. EXAMPLE ROSIA MONTANA GOLD CORPORATION [PDF]

open access: yes
Corporate Social Responsibility, a concept without a world accepted definition is starting to beused in Romania as well. This is the reason why in the present article we try to make a theoreticaldescription of the present concept and to exemplify it by ...
Silvia – Stefania Mihalache   +1 more
core  

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