Results 111 to 120 of about 308,892 (313)

Corporate social responsibility of multinational companies in Pakistan [PDF]

open access: yes, 2012
Despite the growing interest of scholars, research on Corporate Social Responsibility (CSR) and the role of the subsidiaries of foreign multinational companies (MNCs) in the context of developing countries is scant.
Yunis, Mohammad
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Heterodox Critiques of Corporate Social Responsibility [PDF]

open access: yes
Corporate social responsibility (CSR) is in vogue in recent times. It has been widely received by socially concerned people in business, academia, and NGOs that CSR would lend support to the improvement in social welfare and the protection of environment.
Jo, Tae-Hee
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

URDU: سیاسی و سماجی معا ملات میں احساسِ ذمہ داری: سیرۃ النبیﷺ کی روشنی میں تعمیری مطالعہ

open access: yesایقان, 2019
Islam readily being a natural religion provides a complete code of conduct to human being. According to Islam, concept of state, the sense of responsibility has too much importance. The essence of responsibility gives birth to social progress and success.
Abdul Rauf   +2 more
doaj   +1 more source

CORPORATIVE SOCIAL RESPONSIBILITY, PARTNER OR OPPONENT OF KNOWLEDGE MANAGEMENT? [PDF]

open access: yes
It appeared as an initiative of the big transnational companies in their fight for the maintaining and the improvement of their competitive position, Corporative Social Responsibility imposes itself nowadays as an innovative concept, usually associated ...
Anca Maria HRISTEA
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

SELF-PROMOTION OF THE MONOGRAPH "OUTLINE OF THE THEORY OF THE STATE AS AN ECOLOGICALLY SAFE ORGANIZATION IN EMPIRICAL RESEARCH"

open access: yesHumanities and Social Sciences
Four concepts – ecological security, social responsibility, sustainable development, and environmental management – are analyzed to show that the same terminology can represent different meanings and approaches to the development of a state or urban ...
Ewa Jadwiga LIPIŃSKA
doaj   +1 more source

The convergence of corporate social responsibility practices [PDF]

open access: yes
Purpose – This paper tries to explain why many socially-responsible firms appear to converge on a standard set of corporate social responsibility (CSR) practices instead of striving to differentiate themselves from rivals and achieve competitive ...
Misani, Nicola
core   +1 more source

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