Results 131 to 140 of about 2,390,312 (355)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A Research on the Social Responsibility Efficiency of Chinese Listed Food Companies
Acta Universitatis Cibiniensis. Series E: Food Technology, 2017 On the basis of establishing an input-output index system of listed food companies’ social responsibility, this paper uses the DEA model to assess 22 Chinese listed food companies’ social responsibility efficiency between 2014 and 2016. Results show that
Zhang Weimei
doaj +1 more source
Efektivitas Pelaksanaan Program Tanggung Jawab Sosial Perusahaan PT. Pertamina (Persero) Unit Pemasaran I Medan di Lingkungan XII Kelurahan Silalas Kecamatan Medan Barat [PDF]
, 2013 PT. Pertamina (Persero) Unit Pemasaran I Medan is a well known State Owned Corporation with operation for marketing and distributing the product of downstream manufacturing of oil, gas and natural petroleum.
M, D. M. (DHAHRAN)
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Master model on multi-actor and multilevel social responsibilities [PDF]
, 2011 This working paper contributes to a collective discussion in a workshop occurring in January 2011 at the International Institute of Social Studies, bringing scholars from Europe and Brazil and aiming inter-university research collaboration on linking ...
Ashley, P.A. (Patricia Almeida)
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Legal regulations corporate social responsibility in Ukraine needs improvement [PDF]
, 2016 Розглянуто значення соціальної відповідальності бізнесу для розквіту суспільства і держави в цілому. Висвітлено особливості розвитку в Україні корпоративної соціальної відповідальності та діючі законодавчо-нормативні акти, що прямо чи опосередковано ...
Burkovskaya, Alla +3 more
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Baden-Powell’s Scouting for Boys : governmentality, state power and the responsibilization of youth [PDF]
This paper will focus on two issues – those of responsibility, and how state power has gone through a transformation, from, as Simon Gunn has put it, ‘hegemony to governmentality’, and also on the impact of social class on ideas of participation for ...
Dean, Jonathan
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