Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The motherhood penalty and absence of leisure rights: legal examination and institutional response under China's three-child policy. [PDF]
Huang T, Hu Z.
europepmc +1 more source
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source
The 2025-2030 US Dietary Guidelines: an analysis of scientific integrity and global health governance. [PDF]
Neves FS +4 more
europepmc +1 more source
Do Female State Officials Improve Corporate Social Responsibility in their Jurisdictions? A Disadvantage‐Prohibiting Perspective [PDF]
Jian Chu, H. J. Wang, Guoguang Wan
openalex +1 more source
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
Are the Australian Dietary Guidelines Fit for Purpose for Culturally Diverse Populations? A Qualitative Study. [PDF]
Narsh H, Gallegos D.
europepmc +1 more source
Functions of the State in the Implementation of Social Responsibility by State-Owned Enterprises
Nurhaedah Nurhaedah +3 more
openaire +1 more source
CORPORATE SOCIAL RESPONSIBILITY IN THE MODERN STATE: MORAL FUNDAMENTALS AND DEVELOPMENT
M.I. Rudakevych, O.M. Rudakevych
openalex +1 more source

