Results 231 to 240 of about 13,797,006 (300)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

International fiscal architecture for advancing sexual and reproductive health and rights.

BMJ
Waris A, Bohoslavsky JP, Ooms G, Hammonds R.   +3 more
europepmc   +1 more source

Tracing governance transitions: A qualitative framework for analysing shifts from rights-based to entrepreneurial governance regimes. [PDF]

MethodsX
Sahide MAK, Daben MC, Sirimorok N, Santika T.   +3 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Navigating technology-facilitated abuse: A participatory action research study with young adults living with HIV and key populations in Kenya. [PDF]

PLOS Glob Public Health
Macharia JN, Kiilu J, Odiwuor S, Gift W, Wafula T, Koomson B, Davis SLM.   +6 more
europepmc   +1 more source

Work as a crime, a resource and a relationship: the confiscation of wages as proceeds of crime. [PDF]

Crime Law Soc Change
Niezna M.
europepmc   +1 more source

Witchcraft accusations against older women in Sub-Saharan Africa: a narrative review and community-based inclusive development framework synthesis. [PDF]

Front Public Health
Chung EY, Makponga I.
europepmc   +1 more source

Disability inclusion as a missing pillar of Africa's non-communicable disease response. [PDF]

BMJ Glob Health
Seidu AA, Osborne A, Agbadi P, Ganle JK, Baatiema L, Naami A, Malabu U, Agyemang C, Sambah F, Emeto TI.   +9 more
europepmc   +1 more source

Workforce Science and the Human-AI economy of health and care. [PDF]

PLOS Glob Public Health
Campbell J.
europepmc   +1 more source