Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Secure accommodation in Scotland : its role and relationship with 'alternative' services. [PDF]
, 2005 This Scottish Executive funded study of secure accommodation and services which offer an alternative was carried out between November 2002 and 2005, by a research team from the universities of Stirling, Strathclyde and Glasgow.
Hunter, L. +14 more
core
National Social Science Survey, 1995/96
, 2019 This file is the eighth in the National Social Science Survey (NSSS) series and repeats many of the questions asked in previous rounds. The survey includes questions asked as part of the International Social Survey Programme.
Bean, Clive +2 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
A global network of social movements? An approach to the cycle of protests 2011-2013 [PDF]
, 2013 The social protests that have take place in many countries over the past three years - from Tunisia and the so-called Arab Spring to the recent protests in Turkey and Brazil - have given rise to a debate about the possible global and transnational ...
Mateos, Oscar
core
Magnetoencephalography Hyperscanning Evidence of Differing Cognitive Strategies Due to Social Role During Auditory Communication. [PDF]
Front Neurosci, 2022 Yoneta N +8 more
europepmc +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Social enterprise networks and social capital: A case study in Scotland/UK [PDF]
, 2014 The chapter focuses on how social aims and cooperative attitudes have been supported in the shaping of networks in Scotland, and why this is relevant for the sustainable development of social enterprise and communities. From this background, our main aim
Campbell, Colin, Sacchetti, Silvia
core
THE MODERN CONDITION OF PROBLEM OF EMOTIONAL BURNOUT IN THE PSYCHOLOGICAL SCIENCE
Вестник университета, 2019 The article describes the emotional burnout. The author’s analyzes various theories and come to the conclusion that various factors at work can lead this syndrome. In addition, the article reveals the ways how to fight this syndrome - the different kinds
V. Knyazev, K. Remizova
doaj
Loss of perceived social role, an index of social frailty, is an independent predictor of future adverse events in hospitalized patients with heart failure. [PDF]
Front Cardiovasc Med, 2022 Watanabe A +13 more
europepmc +1 more source