Results 111 to 120 of about 2,524,397 (315)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2004 'Mitte November 2003 (14.-15.11.2003) organisierte das Informationszentrum Sozialwissenschaften, Abteilung Informationstransfer Osteuropa, einen Workshop zum Thema 'The East European Social Sciences: Research Conditions and the Role of Information ...
Informationszentrum Sozialwissenschaften, Bonn (Germany)
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The Role of Morality in Social Cognition
, 2019 Over the past few decades, two-factor models of social cognition have emerged as the dominant framework for understanding impression formation. Despite the differences in the labels, there is wide agreement that one dimension reflects sociability potential, and the other, competence.
Jennifer Lauren Ray +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Owner's Anthropomorphic Perceptions of Cats' and Dogs' Abilities Are Related to the Social Role of Pets, Owners' Relationship Behaviors, and Social Support. [PDF]
Animals (Basel), 2023 Bouma EMC, Dijkstra A, Arnt Rosa S.
europepmc +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Finding normal-to-better neurocognitive indexes in individuals with schizotypal traits using a social role task. [PDF]
Schizophrenia (Heidelb), 2023 Diao M +4 more
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Social work in dark places : clash of values in offshore immigration detention
, 2016 Social work practice in offshore detention sites is a contested area in Australia. From first-hand experience, this article examines the dilemmas facing a caseworker during the time she was employed by a non-government organisation in Nauru, where ...
Briskman, Linda (R18870), Doe, Jane
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The social role of defective viral genomes in chronic viral infections: a commentary on Leeks et al. 2023. [PDF]
J Evol Biol, 2023 Zhao L, Lythgoe KA.
europepmc +1 more source