Results 161 to 170 of about 1,605,755 (265)

(Re)Conceptualizing Sex and Gender in Physical Education through Social Role Theory. [PDF]

Quest
Moss AC, Chen A.
europepmc   +1 more source

[Alcohol as cultural asset-a historical, anthropological, and therapeutic perspective on alcohol consumption and its social role in western societies]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2021
Heinz A, Daedelow LS.
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Short-term changes in social role statuses across young adulthood and their relation to heavy drinking in a given month. [PDF]

J Res Adolesc
Fairlie AM, Calhoun BH, Walukevich-Dienst K, Janson M, Patrick ME, Lee CM.   +5 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Perceptions of formal pharmacy leadership on the social role of the profession and its historical evolution: A qualitative study. [PDF]

Explor Res Clin Soc Pharm
Araújo-Neto FC, Dosea AS, Fonseca FLD, Tavares TMA, Santos DM, Pimentel DMM, Mesquita AR, Lyra DP.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Social Role-Related Stress and Social Role-Related Reward as Related to Subsequent Subclinical Cardiovascular Disease in a Longitudinal Study of Midlife Women: The Study of Women's Health Across the Nation. [PDF]

Psychosom Med, 2019
Stewart AL, Barinas-Mitchell E, Matthews KA, El Khoudary SR, Magnani JW, Jackson EA, Brooks MM.   +6 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Social role functioning in Parkinson's disease: A mixed-methods systematic review. [PDF]

Int J Geriatr Psychiatry, 2019
Perepezko K, Hinkle JT, Shepard MD, Fischer N, Broen MPG, Leentjens AFG, Gallo JJ, Pontone GM.   +7 more
europepmc   +1 more source