Results 181 to 190 of about 2,524,397 (315)

Building and Repairing Trust in Chatbots: The Interplay Between Social Role and Performance During Interactions. [PDF]

Behav Sci (Basel)
Mou Y, Ye X, Ma W.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

How the self-concept structures social role learning: insights from computational models. [PDF]

R Soc Open Sci
Garcia-Arch J, Sabio-Albert M, Korn CW, Fuentemilla L.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Can Australian local government play a meaningful role in the development of social capital in disadvantaged rural communities?

, 2000
There is now widespread acceptance of the critical role social capital and its attendant dimension of a ‘sense of place’ can play in nurturing poor rural communities and in reversing the current trend towards growing regional economic and social ...
Worthington, Andrew C., Dollery, Brian E.   +1 more
core  

Self-control has a social role in primates, but not in other mammals or birds. [PDF]

Sci Rep
Dunbar RIM, Shultz S.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Social work as narrative: An investigation of the social and literary nature of social work accounting

, 1993
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis investigates what can be gained by approaching social work reports and conversations as narratives.
Hall, Christopher J, Hall, C.J
core  

The mediating role of PERMA in the relationship between social role engagement and drug use problems among veterans with mental illness. [PDF]

Front Psychiatry
Campa R, Solis GR, Koc M, Granger TA, Lee B, Umucu E.   +5 more
europepmc   +1 more source

Social Role [PDF]

, 2020
openaire   +1 more source