Results 181 to 190 of about 16,775,741 (374)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Polygenic scores for social science: Clarification, consensus, and controversy. [PDF]
Behav Brain Sci, 2023 Burt CH.
europepmc +1 more source
Commission government number of “the annals.” November, 1911. Issued by the American Academy of Political and Social Science. Philadelphia. $1.00 [PDF]
, 1912 Francis W. Dickey
openalex +1 more source
e-Science Infrastructure for the Social Sciences [PDF]
When the term „e-Science“ became popular, it frequently was referred to as “enhanced science” or “electronic science”. More telling is the definition ‘e-Science is about global collaboration in key areas of science and the next generation of ...
Ekkehard Mochmann
core
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Book Reviews and Notes : LUXURY. No. 24, Social Science Series. By EMILE DE LAVELEYE. London : Swan, Sonnenschein & Co., I89I [PDF]
, 1891 John J. Halsey
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source