Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Intimidation as epistemological violence against social science conservation research. [PDF]
Conserv BiolKoot S +16 more
europepmc +1 more source
"Economy and Trade." The Address of the President of the Department IV of the National Association for the Promotion of Social Science, Held at Huddersfield in October, 1883 [PDF]
, 1883 Joel Rogers
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Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Insights on human-wildlife coexistence from social science and Indigenous and traditional knowledge. [PDF]
Conserv BiolJolly H, Stronza A.
europepmc +1 more source
A social science research agenda to accelerate public engagement in climate change adaptation. [PDF]
Front Psychol, 2023 Harcourt R +3 more
europepmc +1 more source
Address of the President of the Department of "Economy and "Trade" Section National Association for the Promotion of Social Science, at the Twentieth Annual Congress, Held at Liverpool, in October, 1876 [PDF]
, 1876 G. J. Shaw Lefevre
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Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Social and International Relations of Science [PDF]
, 1938 G Af, George Whitby
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ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source