Results 251 to 260 of about 1,378,917 (312)

EPH-International Journal of Humanities and Social Science

open access: diamond
Neha Kardam   +5 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Design and context of use of postpartum haemorrhage kits in the UK: a qualitative study combining human factors and social science analysis

open access: yes
Woodward M   +8 more
europepmc   +1 more source

A guide for social science journal editors on easing into open science. [PDF]

open access: yesRes Integr Peer Rev
Silverstein P   +38 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Co-production of health and social science research with vulnerable children and young people: A rapid review. [PDF]

open access: yesHealth Expect
Erwin J   +12 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy