Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Identifying Strategies for Strengthening Behavioral and Social Science Research Study Conduct. [PDF]
Murphy SL+3 more
europepmc +1 more source
John E. Pomfret
openalex +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Perpetuating global inequalities in the knowledge economy: The case of HIV social science research in East Africa. [PDF]
Wight D.
europepmc +1 more source
Investigations in Progress in the United States in the Field of Latin-American Humanistic and Social Science Studies [PDF]
Madaliné W. Nichols
openalex +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
A social science trust taxonomy with emergent vectors and symmetry. [PDF]
Mobbs AED, Boag S.
europepmc +1 more source