Results 31 to 40 of about 11,191,782 (263)
FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
Towards the social media studies of science: social media metrics, present and future [PDF]
Bibliotecas. Anales de Investigacion. 2017. 13(1), 1-5, 2018 In this paper we aim at providing a general reflection around the present and future of social media metrics (or altmetrics) and how they could evolve into a new discipline focused on the study of the relationships and interactions between science and social media, in what could be seen as the social media studies of science.
arxiv
Analytical sociology and computational social science
Journal of Computational Social Science, 2017 Analytical sociology focuses on social interactions among individuals and the hard-to-predict aggregate outcomes they bring about. It seeks to identify generalizable mechanisms giving rise to emergent properties of social systems which, in turn, feed ...
Marc Keuschnigg +2 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Self-organization and social science
Computational and mathematical organization theory, 2017 Complexity science and its methodological applications have increased in popularity in social science during the last two decades. One key concept within complexity science is that of self-organization. Self-organization is used to refer to the emergence
D. Anzola +2 more
semanticscholar +1 more source
FEBS Letters, EarlyView.We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin +2 more
wiley +1 more source
Analysis and Predictions of Social Phenomena via social media using Social Physics method [PDF]
arXiv, 2017 As a method of analyzing and predicting social phenomena using social media as data, we propose a method using a mathematical model of hit phenomenon which is the theory of social physics. I could explain the transition of the number of social media written in movies, TV dramas, Music Concerts, Pokemon GO and proposed a method that can be used for ...
arxiv
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Two Types of Social Grooming Methods depending on the Trade-off between the Number and Strength of Social Relationships [PDF]
arXiv, 2017 Humans use various social bonding methods known as social grooming, e.g. face to face communication, greetings, phone, and social networking sites (SNS). SNS have drastically decreased time and distance constraints of social grooming. In this paper, I show that two types of social grooming (elaborate social grooming and lightweight social grooming ...
arxiv