Results 91 to 100 of about 6,206,849 (362)
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Graduate School of Humanities & Social Sciences
core +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
"Hard Sciences" e "Social Sciences": Um Enfoque Organizacional
The article offers an empirically guided discussion of the organizational model which Whitley has proposed for analyzing scientific fields. The central, empirically tested dimensions of the model refer to a consensus-forming process.
Beato F. Claudio C.
doaj
https://nsuworks.nova.edu/shss_dialogs/1021/thumbnail ...
Graduate School of Humanities & Social Sciences
core +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Information Science: Science Or Social Science?
Collection, selection, processing, management, and dissemination of information are the main and ultimate role of Information Science and similar studies such as Information Studies, Information Management, Library Science, and Communication Science and so on.
Sreeramana Aithal +2 more
openaire +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Expectations guide predictive eye movements and information sampling during face recognition
Summary: Context information has a crucial impact on our ability to recognize faces. Theoretical frameworks of predictive processing suggest that predictions derived from context guide sampling of sensory evidence at informative locations. However, it is
Annika Garlichs +3 more
doaj +1 more source

