Results 131 to 140 of about 6,071,023 (341)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The Elements of Social Science; Or Physical, Sexual and Natural Religion. An Exposition of the True Cause and Only Cure of the Three Primary Social evils, Poverty, Prostitution and Celibacy [PDF]

, 1890
George R. Drysdale
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Early warning of regime switching in a complex financial system from a spillover network dynamic perspective

iScience
Summary: Early warning of regime switching in a complex financial system is a critical and challenging issue in risk management. Previous research has examined regime switching through analyzing the fluctuation features in a single point in time series ...
Sufang An, Xiangyun Gao, Feng An, Tao Wu
doaj  

Explanation and Understanding Revisited [PDF]

, 2017
"Explanation and Understanding" (1971) by Georg Henrik von Wright is a modern classic in analytic hermeneutics, and in the philosophy of the social sciences and humanities in general.
Raatikainen, Panu
core   +1 more source

An Experimental Study of the Merits of Extensive and Intensive Reading in the Social Sciences [PDF]

, 1925
Carter V. Good
openalex   +1 more source

Socials science [PDF]

Nature Plants, 2020
openaire   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Bluetooth-sensed social presence is associated with immediate vigor and delayed fatigue: A multi-method time series analysis

iScience
Summary: Social interactions affect emotional well-being, yet their temporal dynamics remain understudied in natural settings. We examined these patterns through an experience sampling method study with 80 participants over two weeks (k = 3,716 ...
David Willinger, Stefan Stieger
doaj  

Statistical Analysis of Humanities and Social Sciences Collaboration Research in China [PDF]

, 2006
With the development of humanities and social sciences, research collaboration becomes more and more important. This article studies collaboration phenomena of seventeen kinds of journals’ from 1995-2004 in china.
Chunlin, Jiang, Yongxia, Liang
core