Results 221 to 230 of about 12,433,729 (358)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Pandemic preparedness: why humanities and social sciences matter. [PDF]

Front Public Health
Frampton S, Orievulu K, Matthews PC, Giubilini A, Hordern J, Burns L, Elias S, Friederich E, Majozi N, Martin S, Stevenson A, Vanderslott S, Seeley J.   +12 more
europepmc   +1 more source

ECRIN - CESSDA strategies for cross metadata mappings in selected areas between life sciences and social sciences and humanities. [PDF]

Open Res Eur, 2023
Ohmann C, Moilanen K, Kleemola M, Canham S, Panagiotopoulou M.   +4 more
europepmc   +1 more source

Methods matter: Exploring how expectations influence common actions

iScience
Summary: Behavior in controlled laboratory studies is not always representative of what people do in daily life. This has prompted a recent shift toward conducting studies in natural settings.
Andrea Ghiani, David Mann, Eli Brenner
doaj  

"Economy and Trade." The Address of the President of the Department IV of the National Association for the Promotion of Social Science, Held at Huddersfield in October, 1883 [PDF]

, 1883
Joel Rogers
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

The BSSO Foundry: A community of practice for ontologies in the behavioural and social sciences. [PDF]

Wellcome Open Res
Hastings J, Zhang L, Schenk P, West R, Gehrke B, Hogan WR, Chorpita B, Johnston M, Marques MM, Webb TL, Baird HM, Crombez G, Michie S.   +12 more
europepmc   +1 more source

Toward Coequality of the Social Sciences in the National Climate Assessment. [PDF]

Weather Clim Soc, 2022
Maxwell K, Eisenhauer E, Lustig A.
europepmc   +1 more source

Address of the President of the Department of "Economy and "Trade" Section National Association for the Promotion of Social Science, at the Twentieth Annual Congress, Held at Liverpool, in October, 1876 [PDF]

, 1876
G. J. Shaw Lefevre
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source