Results 181 to 190 of about 777,270 (359)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

DASSH response to the Department of Education and Training’s consultation paper [PDF]

DASSH endorses the emphasis on simplifying systems and reporting requirements, incentivising engagement with end-users, and recognising that Australia has a mature university system in which individual higher education institutions should determine the ...
Australasian Council of Deans of Arts, Social Sciences and Humanities   +1 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Correction: Children's right to play in Chilean hospitals: A forgotten right?-A qualitative study protocol. [PDF]

PLoS One
Głos A, López AS, Celis IV, Díaz LS, Quezada C.   +4 more
europepmc   +1 more source

Understanding collaborative interactions in relation to research impact in social sciences and humanities: A meta-ethnography

, 2020
Alexis Dewaele, Kristof Vandael, Stefan Meysman, Ann Buysse   +3 more
openalex   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Correction: Healthcare quality evaluation of tertiary public hospitals in ethnic border regions under China's performance assessment system-based on the entropy weight TOPSIS method and RSR fuzzy set. [PDF]

Front Public Health
Huang J, Wu Y, Pan H, Yuan H, Liu X, Wang H, Zeng P, Tang Z, Zhu P.   +8 more
europepmc   +1 more source

The ESF Scoping Project ‘Towards a Bibliometric Database for the Social Sciences and Humanities’ [PDF]

, 2016
Gerhard Lauer
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Editorial: Mobilities, migration, and digital humanities. [PDF]

Front Sociol
Chaudhuri M, Chattopadhyay C, Menon N, Arthur PL, Kenderdine S, Rischard M, Shanmugapriya T.   +6 more
europepmc   +1 more source