Results 181 to 190 of about 353,000 (306)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

[A look at the potential of the Social Sciences and Humanities to face the challenges facing Public Health]. [PDF]

Cad Saude Publica
Brandão ER.
europepmc   +1 more source

Health professionals prepared for the future. Why Social Sciences and Humanities teaching in Medical Faculties matter. [PDF]

MedEdPublish (2016), 2018
Lechopier N, Moutot G, Lefève C, Teixeira M, Poma R, Grandazzi G, Rasmussen A.   +6 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Patterns of internationalization and criteria for research assessment in the social sciences and humanities. [PDF]

Scientometrics, 2016
Sivertsen G.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Humanities, Arts, and Social Sciences, Social-Media and Social Networking: Good Governance

Shodh Sari
Every society understands civilization as well as development based on humanity, social relationship, responsible social media and social networking. It is a very crucial point to discuss at present time the relevancy and significance of humanities, art ...
Arti
doaj  

The first nationwide survey of MD-PhDs in the social sciences and humanities: training patterns and career choices. [PDF]

BMC Med Educ, 2017
Holmes SM, Karlin J, Stonington SD, Gottheil DL.   +3 more
europepmc   +1 more source

Humanities and social sciences and the Polar Regions [PDF]

The Polar Journal, 2018
openaire   +2 more sources

OAPEN-UK: an Open Access Business Model for Scholarly Monographs in the Humanities and Social Sciences [PDF]

This paper presents the current findings of OAPEN-UK, a UK research project gathering evidence on the social and technological impacts of an open access business model for scholarly monographs in the humanities and social ...
Milloy, Caren, Collins, Ellen, Stone, Graham   +2 more
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