Results 121 to 130 of about 3,824,520 (347)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

The Problems of LLM-generated Data in Social Science Research [PDF]

open access: yesSociologica
Funding Agencies|Wallenberg AI, Autonomous Systems and Software Program - Humanity and Society (WASP-HS) - Marianne and Marcus Wallenberg ...
Rossi, Luca   +2 more
openaire   +4 more sources

The Ethical Dimension of Economic Choices [PDF]

open access: yes
In general, capitalist countries display sustained growth, dynamism and innovation, and a high adaptability in response to external shocks. Yet in the last twenty years discontent over the notorious drawbacks of capitalism – corporate frauds, corruption,
Vranceanu, Radu
core   +1 more source

Resource Guide in Exploring Ethics: A Practical Resource Guide for Tutors and Students [PDF]

open access: yes, 2009
This resource guide will help staff and students who are studying social sciences in hospitality, tourism, entertainment, events, leisure. It outlines the ethical issues that they need to consider when conducting research for their dissertation or for ...
Kenyon, AJ, Wood, E
core  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

How Preferences of General Medicine Students for Specialty Choice Are Affected? a qualitative study

open access: yesپژوهش‌های سلامت‌محور, 2019
How Preferences of General Medicine Students for Specialty Choice Are Affected? a qualitative study   Heidari Mehdi1, Keivanara Mahmood2, Moeeni Maryam3*   1.
Mehdi Heidari   +2 more
doaj  

The cost of fiscal subsidies to higher education students in South Africa: A comparison between 2000 and 2006 [PDF]

open access: yes
In this analysis the expenditure (subsidy) on higher education institutions (HEIs) in South Africa is compared for 2000 and 2006. The analysis was done with headcounts of students as well as with full-time equivalent student numbers.
Pierre de Villiers
core  

Modeling and control in physical, life, and social sciences: Some remarks [PDF]

open access: yes, 2014
International audienceMathematical —or mathematico-numerical— models have pervaded all branches of knowledge, and once control theoreticians have become mainly model-builders.
Bernhard, Pierre
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

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