Results 111 to 120 of about 1,315,491 (307)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Subcommittee on Economic and Social Sciences (SCESS) - 15th Session. Report [PDF]

, 2015
The fifteenth session of the Subcommittee on Economic and Social Sciences (SCESS) of the GFCM Scientific Advisory Committee (SAC) addressed the following topics: i) socioeconomic assessments in selected case studies; ii) estimation and submission of ...
GFCM - SCESS (General Fisheries Commission for the Mediterranean- Subcommittee on Economic and Social Sciences)
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Logic of the Method of Agent-Based Simulation in the Social Sciences: Empirical and Intentional Adequacy of Computer Programs [PDF]

The classical theory of computation does not represent an adequate model of reality for simulation in the social sciences. The aim of this paper is to construct a methodological perspective that is able to conciliate the formal and empirical logic of ...
Helder Coelho, Jaime Sim�o Sichman, Nuno David   +2 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

THE NIGERIAN JOURNAL OF THE SOCIAL SCIENCES [PDF]

The Nigerian Journal of the Social Sciences (NUSS), is an official quarterly Journal of the Faculty of the Social Sciences, Ekiti State University, Ado Ekiti, Nigeria.
POPOOLA ADEWALE SHEYI, POPOOLA ADEWALE SHEYI, OLUFUNMI SOLOMON LIKINYO, OLUFUNMI SOLOMON LIKINYO, IGBALAJOBI OLUSOLA JOHNSON , IGBALAJOBI OLUSOLA JOHNSON, IFEYINWA ARUM, IFEYINWA ARUM, Damilola A. OSEKITA, Damilola A. OSEKITA, Adebayo W.O., Adebayo W.O., Adedeji J. OGUNLEYE, Adedeji J. OGUNLEYE, Johnson Oluwole Ayodele , Johnson Oluwole Ayodele, Imole, P O., Imole, P O., CHARLES FOLUSHO AWE, CHARLES FOLUSHO AWE, Adegboyega, Emmanuel , Adegboyega, Emmanuel, OLOFIN, E.O, OLOFIN, E.O, OLUSOLA , J.A, OLUSOLA , J.A, Roda B. GBADEBO, Roda B. GBADEBO, Olayide OLADEJI, Olayide OLADEJI, Owolabi J.T., Owolabi J.T., Ayodeji Peter ADESANYA , Ayodeji Peter ADESANYA, ADEBAYO, W.O., ADEBAYO, W.O., Yekinni, O.S., Yekinni, O.S., Yekinni, Samuel , Yekinni, Samuel, Idris Mohammed , Idris Mohammed, Kemi Ogundana , Kemi Ogundana, Busayo Ade-Ojo , Busayo Ade-Ojo   +22 more
core   +4 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source