Results 161 to 170 of about 3,824,520 (347)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
A study of the potential impacts of space utilization [PDF]
Because the demand for comprehensive impact analysis of space technologies will increase with the use of space shuttles, the academic social sciences/humanities community was surveyed in order to determine their interests in space utilization, to develop
Chafer, C. M. +4 more
core +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
FEBS Open Bio, EarlyView.This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
ETHNOLOGY AND GENERAL: Fact and Theory in Social Science. Earl W. Count and Gordon T. Bowles, eds [PDF]
, 1965 Edward B. Shils
openalex +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
FEBS Open Bio, EarlyView.PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
Il ruolo dell’improvvisazione e della narrazione nelle scienze sociali, nell’arte e nella creatività
Narrare i Gruppi, 2019 The role of improvisation and storytelling in the social sciences, art and creativity ----- Abstract --- The concept of improvisation has become increasingly popular in organizational theory.
Alfonso Montuori
doaj
The Structural-Genetic Theory Programme as General Theory to Social Sciences [PDF]
Georg W. Oesterdiekhoff
openalex +1 more source
On the capitalization and cultivation of social capital: Towards a neo-capital general science? [PDF]
, 2007 Christian Waldstrøm +1 more
openalex +1 more source