Results 31 to 40 of about 2,110,914 (308)
FEBS Letters, EarlyView.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
FEBS Letters, EarlyView.The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet +4 more
wiley +1 more source
Investigation of anxiety and depression in patients with chronic diseases
Health Psychology Research, 2015 The health of an individual depends on both his/her physical and psychological condition. In recent years it has been observed that chronic patients have frequently an affected psycho-emotional state.
Evangelia-Ioanna Gerontoukou +4 more
doaj +1 more source
The Sociological Study of the Process of Professional Identity Formation in Doctoral Students of Social Sciences in Iran [PDF]
Interdisciplinary Studies in the Humanities, 2019 Professional identity refers to a process that answers the question "who am I" during One has been studying for years at university. The PhD is the latest stage in the development of this kind of identity that has a great bearing on the career path of ...
G. Jafari +2 more
doaj +1 more source
Generalized Markovian Quantity Distribution Systems: Social Science Applications [PDF]
Sociological Science, 2020 We propose a model of Markovian quantity flows on connected networks that relaxes several properties of the standard compartmental Markov process. The motivation of our generalization are social science applications of the standard model that do not comport with its steady state predictions.
Friedkin, Noah, Proskurnikov, Anton
openaire +5 more sources
Social Science Theories in Software Engineering Research [PDF]
arXiv, 2022 As software engineering research becomes more concerned with the psychological, sociological and managerial aspects of software development, relevant theories from reference disciplines are increasingly important for understanding the field's core phenomena of interest. However, the degree to which software engineering research draws on relevant social
arxiv
Social Recommendations within the Multimedia Sharing Systems [PDF]
Musial K., Kazienko P., Kajdanowicz T.: Social Recommendations
within the Multimedia Sharing Systems. The First World Summit on the
Knowledge Society, WSKS'08, Lecture Notes in Computer Science LNCS 5288,
2008, pp. 364-372, 2013 The social recommender system that supports the creation of new relations between users in the multimedia sharing system is presented in the paper. To generate suggestions the new concept of the multirelational social network was introduced. It covers both direct as well as object-based relationships that reflect social and semantic links between users.
arxiv +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source