Results 41 to 50 of about 2,110,914 (308)
Inverse Generative Social Science: Backward to the Future
Journal of Artificial Societies and Social Simulation, 2023 The agent-based model is the principal scientific instrument of generative social science. Typically, we design completed agents-fully endowed with rules and parameters-to grow macroscopic target patterns from the bottom up. Inverse generative science (iGSS) stands this approach on its head: Rather than handcrafting completed agents to grow a target ...
openaire +2 more sources
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Domain-based user embedding for competing events on social media [PDF]
arXiv, 2023 Online social networks offer vast opportunities for computational social science, but effective user embedding is crucial for downstream tasks. Traditionally, researchers have used pre-defined network-based user features, such as degree, and centrality measures, and/or content-based features, such as posts and reposts.
arxiv
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Complexity Theory: An Overview with Potential Applications for the Social Sciences
Systems, 2019 Systems theory has been challenged in the recent literature due to its perceived disconnection from today’s research and practice demands. Moving away from the reductionist frameworks and the complicated domain predominated by known unknowns and ...
John R. Turner, Rose M. Baker
doaj +1 more source
Generative Adversarial Networks in Business and Social Science
Applied SciencesGenerative adversarial networks (GANs) have become a recent and rapidly developing research topic in machine learning. Since their inception in 2014, a significant number of variants have been proposed to address various topics across many fields, and they have particularly excelled not only in image and language processing but also in the medical and ...
África Ruiz-Gándara +1 more
openaire +3 more sources
Data Science for Social Good [PDF]
arXiv, 2023 Data science has been described as the fourth paradigm for scientific discovery. The latest wave of data science research, pertaining to machine learning and artificial intelligence (AI), is growing exponentially and garnering millions of annual citations.
arxiv
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source