Results 71 to 80 of about 4,056,302 (306)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Forest Ecosystem Services: An Analysis of Worldwide Research [PDF]
The relevance of forests to sustain human well-being and the serious threats they face have led to a notable increase of research works on forest ecosystem services during the last few years.
Aznar Sánchez, José Antonio +3 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Plus largement, les sciences sociales…
The position presented in this paper can be summarized very simply: the future of sociology depends on the future of social sciences in general. This position implies a reflection on the specific features and contours of social sciences, in what forms ...
Michel Grossetti
doaj
Individuals and Organizations Thoughts on a Micro-Foundations Project for Strategic Management and Organizational Analysis [PDF]
Making links between micro and macro levels has been problematic in the social sciences, and the literature in strategic management and organization theory is no exception.
Nicolai Foss, Teppo Felin
core
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Game Theory: The Language of Social Science? [PDF]
The present paper tries in a largely non-technical way to discuss the aim, the basic notions and methods as well as the limits of game theory under the aspect of providing a general modelling method or language for social sciences.
Walter Trockel
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Ghoncheh Raheb,1,2 Esmat Khaleghi,1 Amir Moghanibashi-Mansourieh,1 Ali Farhoudian,2 Robab Teymouri3 1Department of Social Work, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran; 2Substance Abuse and Dependence Research Center ...
Raheb G +4 more
doaj
Dimensions of Memory in Elderly Compared with Non-Elderly [PDF]
Growing old causes significant effects on cognitive and metacognitive processes and increases the likelihood of cognitive failure. The present study aimed to investigate various dimensions of memory in the elderly and compare it with non-elderly.
Kamran Yazdanbakhsh +3 more
doaj

