Results 71 to 80 of about 4,094,474 (305)

L’historien et les archives. L’histoire : vestiges et pratiques des temps modernes au temps présent

open access: yesCahiers François Viète, 2005
Within the framework of a general reflection on the birth of the historical sciences, this article of synthesis wished to start from the question of the scientificity of the social sciences by reflecting on the status of the archives which, for the ...
Marie Thébaud-Sorger
doaj   +1 more source

Language and argumentation in the controversy economic [PDF]

open access: yes
This article offers an approach to the general structure of the controversy in economy. In our case we adopted a perspective to study a particular aspect of the rhetoric that comes from the context of a particular controversy: the controversy on the ...
Estrada, Fernando
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The fate of ethnography : native social science in the English-speaking Caribbean

open access: yesNWIG, 1992
Reviews the research tradition in the social sciences in the post-War Anglophone Caribbean. Painting a general picture of the intellectual climate in the social sciences divisions of the UWI, Carnegie concludes that most studies have dealt with economic ...
Charles V. Carnegie
doaj  

Reorienting fisheries economics education in India [PDF]

open access: yes
Social sciences act as catalysts for Biological sciences. The implications of social sciences whether it be extension, economics, statistics or any other discipline, had taken a long stride in its development and applicability from its general nature ...
Biradar, R S   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Plus largement, les sciences sociales…

open access: yesSociologies, 2012
The position presented in this paper can be summarized very simply: the future of sociology depends on the future of social sciences in general. This position implies a reflection on the specific features and contours of social sciences, in what forms ...
Michel Grossetti
doaj  

Causal Depth: Aspects of a Scientific Realist Approach to Causal Explanation contra Humean Empiricism [PDF]

open access: yes
The purpose of this note is to clarify how the idea of "causal depth" can play a role in finding the more "approximately true" explanation through causal comparisons.
Khan, Haider
core  

What do faculties specializing in brain and neural sciences think about, and how do they approach, brain-friendly teaching-learning in Iran? [PDF]

open access: yes
Objective: to investigate the perspectives and experiences of the faculties specializing in brain and neural sciences regarding brain-friendly teaching-learning in Iran. Methods: 17 faculties from 5 universities were selected by purposive sampling (2018).
Akbarfahimi, Malahat   +2 more
core   +1 more source

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