Results 91 to 100 of about 5,370,301 (294)
BMC Health Services ResearchBackground Population risk stratification (RS) tools have been proposed to tailor interventions, prioritize resources, and proactively manage high-risk individuals with chronic diseases in primary care settings.
Davide Golinelli +9 more
doaj +1 more source
Recent trends for social enterprises in the United Kingdom [PDF]
, 2013 In this presentation I want to provide you with a picture of some of the trends that are developing for social enterprises in the United Kingdom (U.K.). Social enterprise are becoming an increasingly important part of the U.K.
Durkin, Chris
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Access to Childcare and Home Care Services across Europe. An Analysis of the European Union Statistics on Income and Living Conditions (EU SILC), 2016. Social Inclusion Report No 8. September 2019 [PDF]
, 2019 This report uses EU-SILC data for 2016 to examine differences by social risk group and social class in access to care services – specifically, childcare and home care for people with an illness or disability.
Grotti, Raffaele +3 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Efforts Targeting Factors of Health Disparities that Impair HIV Treatment Engagement
Florida Public Health Review, 2019 Health disparities exist in Northeast Florida. Some locations experience morbidities at higher rates than others. Health zone 1 is a prime example. Differences in disease rates are interlaced with the social determinants of health, (SDOH).
Graham F Watts, Sr., Heather Vaughan
doaj
SOCIALIZE - Socialize forum service
, 2018 Socialize Forum is a web service that enables elderly to actively participate and to question for issues of public interest related seniors. To this end, the web interface and the application functioning is appositely designed to be used by elderly and in particular for those are hostile to the use of technology.
Russo D., Miori V.
openaire +1 more source
Do young people experiencing the transition from children’s services to adult services understand the process and what their choices are? [PDF]
, 2010 This project research examines the understanding that young people who receive services from North Yorkshire Children's Social Care Disabled Children's teams, have of the process of transition to Adult and Community Services.
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