Results 211 to 220 of about 12,386,416 (381)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A Replication and Extension of the PEERS® for Young Adults Social Skills Intervention: Examining Effects on Social Skills and Social Anxiety in Young Adults with Autism Spectrum Disorder

Journal of Autism and Developmental Disorders, 2016
Alana J. McVey, B. Dolan, Kirsten S. Willar, Sheryl S. Pleiss, J. Karst, C. Casnar, C. Caiozzo, Elisabeth M. Vogt, Nakia S. Gordon, A. V. Van Hecke   +9 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Designed physical activities targeting social skills in preschoolers: a meta-analysis. [PDF]

Front Psychol
Yuan Y, Liu W, Yi J, Li X.
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Executive function predicts academic and social skills in autistic kindergartners based on a multimodal approach. [PDF]

J Child Psychol Psychiatry
Choi B, Lee H, Kuhn L, Kim J, Hong SJ, Di Martino A, Gozzi A, Lombardo MV, Morrison FJ, Lord C, Kim SH.   +10 more
europepmc   +1 more source

The Effect of Project-based Collaborative Learning and Social Skills on Learning Outcomes in Biology Learning

, 2019
Fatma Sukmawati, Punaji Setyosarı, Sulton Sulton, Purnomo Purnomo   +3 more
openalex   +2 more sources

Combined Oxytocin and Cognitive Behavioral Social Skills Training for Social Function in People With Schizophrenia

, 2021
Robert W. Buchanan, Deanna L. Kelly, Gregory P. Strauss, James M. Gold, Elaine Weiner, Jennifer Zaranski, Shuo Chen, Frank Blatt, Jason Holden, Eric Granholm   +9 more
openalex   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Parent Employment Status and Race/Ethnicity as Predictors of Social Skills Outcomes in Autistic Children in PEERS^® for Preschoolers. [PDF]

J Korean Acad Child Adolesc Psychiatry
Martinez JL, Hajal NJ, Fisher KL, Turner EC, Moody CT, Laugeson EA.   +5 more
europepmc   +1 more source