Results 71 to 80 of about 28,473,894 (313)

The Global Crisis of the Contemporary Labor Practices as a Source of Reproduction of the Intercultural Conflicts, Social Risk and Social Tension

Вісник Харківського національного університету імені В.Н. Каразіна. Серія: Соціологічні дослідження сучасного суспільства: методологія, теорія, методи, 2019
The article presents the elaborated analytical sociological approach that is aimed at the scientific study of the social determinants of the global crisis of the contemporary labor practices as sources of the new social conflicts, social risk and social ...
Volodymyr Sudakov
doaj   +1 more source

Creation of social space through prayers among Dalits in Kerala, India

Prayer and Politics, 2016
Control over social space was central to the everyday practice of caste in Kerala, India. Caste system in Kerala had evolved extreme forms of control over social space, which was critiqued by European missionaries in the nineteenth century.
Sanal Mohan
semanticscholar   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Recruitment Questionnaire 2024

Pseudonymized survey microdata from the 2024 Recruitment Questionnaire of The Social Study (TSS) — a probability-based panel survey of individuals aged 16+ residing in private households in Belgium.
The Social Study, TSS
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Environmental, health, wellbeing, social and equity effects of urban green space interventions: A meta-narrative evidence synthesis.

Environment International, 2019
BACKGROUND As populations become increasingly urbanised, the preservation of urban green space (UGS) becomes paramount. UGS is not just dedicated recreational space such as public parks, but other types of informal green space are important, for example,
R. Hunter, C. Cleland, Anne Cleary, M. Droomers, B. Wheeler, Danielle Sinnett, M. Nieuwenhuijsen, M. Braubach   +7 more
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

PUSH - Public Space in Social Housing - EU HERA JRP

, 2019
Social housing estates are often problematised as places of segregation and disintegration in European cities, yet they are also potentially a prime locus of integration between people of different cultural origins and social backgrounds.
Laura Lieto
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source