Results 81 to 90 of about 28,473,894 (313)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Piantanida Near Space Balloon Gondola Engineered Drawing and Details

open access: yes
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core   +3 more sources

Parish Structures and the Urban Environment Considered Spatially

open access: yesIn_Bo
The religious topography of German cities diversifies in terms of both the social spaces of faith and the built presence of religions and denominations.
Beate Löffler
doaj   +1 more source

Preschool Children’s and Adults’ Expectations About Interpersonal Space

open access: yesFrontiers in Psychology, 2018
The regulation of interpersonal distance and social space plays a central role in social behavior, and intrusions into personal space often lead to irritations in social interactions.
Markus Paulus
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Gender and Domestic Space in Ahmed Ali's and Krishna Sobti's Novels on Old Delhi

open access: yesIdeas: Journal of English Literary Studies, 2021
Female perspective and agency in Delhi from the 1920s to the 1940s do not usually find mention with regard to novels written about that significant period.
Pallavi Narayan
doaj  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

METAMODERN SOCIOLOGY: LEGITIMIZATION OF THE PRECARIATE IN THE AESTHETIC PARADIGM

open access: yesВісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетії
This article is dedicated to analyzing the social foundations of metamodern culture in the context of transformations in the social space of the early 21st century.
Andrii Artemenko
doaj   +1 more source

Acções prescritivas e estratégicas: A edição como espaço social

open access: yesRevista Crítica de Ciências Sociais, 2009
The aim of this article is to contribute towards an understanding of publishing as a complex social space. This social space is composed of a group of agents that are active constructors within the sphere of ideas and written culture through a ...
Nuno Medeiros
doaj   +1 more source

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