Results 101 to 110 of about 5,760,729 (304)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
COSTUME DESIGN AND SOCIAL STATUS VISUALIZATION IN JAVANESE DANCE AT PURA MANGKUNEGARAN
Paradigma: Jurnal Kajian BudayaThe design of costumes holds a crucial role in visualizing the characters’ social status in Javanese dance. By employing symbolic systems, costume design conveys this status to the audience. This study investigates the relationship between costume design
Sriyadi +3 more
doaj +1 more source
Ahkam: Jurnal Ilmu Syariah, 2015 Mahar Tradition in Muslim Locality: Mahar and Social Structure in Indonesian Muslim Society. Law consists of two fundamentals: moral and formal dimensions. Muslim legal scholars greatly appreciate the interplay of both aspects. Legal positivism separates
Noryamin Aini
doaj +1 more source
Evaluation of a Dutch version of the AIMS2 for patients with rheumatoid arthritis [PDF]
, 1996 DUTCH-AIMS2, a Dutch version of AIMS2 and successor to DUTCH-AIMS, is an instrument to assess health status among patients with rheumatic diseases. It provides measurements of 12 areas of health status on scales for health status proper, satisfaction ...
Houtman, P.M. +5 more
core +2 more sources
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Automobilization in the perception of the population of a large city
RUDN journal of SociologyThe progressive process of automobilization providing a comfortable life entails many negative consequences such as safety risks for the environment and people, limited space for physical movement in the city and traffic jams, the scale of which is ...
M. Yu. Popov, E. N. Tuzhba
doaj +1 more source
Social Status, the Spirit of Capitalism, and the Term Structure of Interest Rates in Stochastic Production Economies [PDF]
This paper studies capital accumulation and equilibrium interest rates in stochastic production economies with the concern of social status. Given a specific utility function and production function, explicit solutions for capital accumulation and ...
Heng-fu Zou, Liutang Gong, Yulei Luo
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Signalling, Social Status and Labor Income Taxes [PDF]
We investigate the effects of introducing a linear labor income tax under the assumptions that individuals have concerns for social status, that they can signal their relative standing by spending on a conspicuous good, and that the tax revenue is ...
Ennio Bilancini, Leonardo Boncinelli
core