Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Do People Who Identify as Popular Become Popular in a New Network? A 9-Month Longitudinal Network Analysis [PDF]
Christopher J. Carpenter +2 more
doaj +1 more source
Flexibility in the social structure of male chimpanzees (Pan troglodytes schweinfurthii) in the Budongo Forest, Uganda. [PDF]
Badihi G +4 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Hierarchy in Mixed Relation Networks: Warfare Advantage and Resource Distribution in Simulated World-Systems [PDF]
Jacob Apkarian +3 more
doaj +1 more source
Becoming urban: How city life shapes the social structure and genetics of ants. [PDF]
Janda M.
europepmc +1 more source
A Study on the Research Network Structure of the Maritime Sector Using Social Network Analysis
김형호 +3 more
openalex +1 more source
Learning mixed social structures [PDF]
Nancy M. Henley, Robert B. Horsfall
openalex +1 more source

