Results 151 to 160 of about 759,921 (266)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Dynamics of Social Networks Following Adolescent Pregnancy [PDF]

Journal of Social Structure, 2018
Elizabeth Humberstone
doaj   +1 more source

Behind the wall: Macrolithic artifacts as testing tools for activities and social structure on a Middle Chalcolithic site in Central Anatolia. [PDF]

PLoS One
Řídký J, Doležalová K, Pilař D, Çaylı P, Demirtaş I, Gülçur S.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

An Analysis of the 'Failed States Index' by Partial Order Methodology [PDF]

Journal of Social Structure, 2013
Lars Carlsen, Rainer Brüggemann
doaj   +1 more source

A supergene-controlling social structure in Alpine ants also affects the dispersal ability and fecundity of each sex. [PDF]

Proc Biol Sci
De Gasperin O, Blacher P, Sarton-Lohéac S, Grasso G, Corliss MK, Nicole S, Chérasse S, Aron S, Chapuisat M.   +8 more
europepmc   +1 more source

Social Structure in a Roma Settlement: Comparison over Time. [PDF]

Int J Environ Res Public Health, 2020
Kozubik M, Filakovska Bobakova D, Rosinsky R, Mojtova M, Tvrdon M, van Dijk JP.   +5 more
europepmc   +1 more source

The influence of fish farm activity on the social structure of the common bottlenose dolphin in Sardinia (Italy). [PDF]

PeerJ, 2021
Frau S, Ronchetti F, Perretti F, Addis A, Ceccherelli G, La Manna G.   +5 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The impact of social structure on breeding strategies in an island bird. [PDF]

Sci Rep, 2020
McDonald GC, Engel N, Ratão SS, Székely T, Kosztolányi A.   +4 more
europepmc   +1 more source