Results 81 to 90 of about 21,617,104 (299)

Emergent social structure is typically not associated with survival in a facultatively social mammal. [PDF]

Biol Lett, 2023
Philson CS, Blumstein DT.
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Social system design methodology for transitioning to a new social structure - a holistic urban living lab approach to the well-being city. [PDF]

Front Sociol, 2023
Kimura A, Haraguchi H, Yamauchi Y, Matsuura K.   +3 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Windy weather drives social structure in wild zebra finches. [PDF]

Mov Ecol
Tyson C, Loning H, Tschirren N, Molenaar E, Snijders L, C Griffith S, Naguib M.   +6 more
europepmc   +2 more sources

Choosing the ‘ß' Parameter When Using the Bonacich Power Measure [PDF]

Journal of Social Structure, 2011
Simon Rodan
doaj   +1 more source

Social structure of perennial Vespula squamosa wasp colonies. [PDF]

Ecol Evol, 2022
Dyson CJ, Crossley HG, Ray CH, Goodisman MAD.   +3 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Do People Who Identify as Popular Become Popular in a New Network? A 9-Month Longitudinal Network Analysis [PDF]

Journal of Social Structure, 2019
Christopher J. Carpenter, Xun Zhu, Rachel A. Smith   +2 more
doaj   +1 more source

The effect of prey abundance and fisheries on the survival, reproduction, and social structure of killer whales (Orcinus orca) at subantarctic Marion Island. [PDF]

Ecol Evol, 2023
Jordaan RK, Oosthuizen WC, Reisinger RR, de Bruyn PJN.   +3 more
europepmc   +1 more source